# Overview The Interactive Variant Analyser (IVA) is the web user interface for [OpenCGA](http://docs.opencb.org/display/opencga/Welcome+to+OpenCGA) that provides unprecedented features for real-time interaction with genomic data. It is suitable for any scale; from the detailed interpretation of a single genomic test through to assessing the genetic diversity of hundreds of thousands of aggregated genomes. It is not just for bioinformaticians; it provides simple and convenient access for biomedical researchers and clinical scientists as well. ### Features * **Variant Browser:** Efficiently browse annotated variants normalised across all samples loaded into a project. Filter variants by multiple criteria including genomic, genetic consequence, population frequency, clinical, phenotype, deleteriousness, and conservation. * **Case Interpreter:** Perform clinical interpretation of cases; singletons, families, cancer from panels, exomes and whole genomes, and record your interpretation findings directly into OpenCGA. * **Variant Analysis:** Access a variety of analysis and QC tools, run asynchronously, at sample, individual and population level. * **Alignment Browser:** interactively and smoothly visualise the genomic alignments (BAM/CRAM) associated with your samples. * **Catalog Browser:** browse the files, samples, individuals and families associated with your studies ### Benefits * **Authenticated** and **secure** platform to query and visualise data * Highly **customisable;** extensible though **plugins** IVA has been developed as part of the [OpenCGA](http://docs.opencb.org/display/opencga/Welcome+to+OpenCGA) project, making it easy to work with clinical and variant information stored in a Catalog and Variant storage instance. {% hint style="success" %} **Rich Configuration** 💡 Administrators can highly customise their IVA installation through a rich set of configuration options. You can easily customise the navigation bar, welcome page, filters and many other aspects of the interface. {% endhint %} --- # Agent Instructions: Querying This Documentation If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question. Perform an HTTP GET request on the current page URL with the `ask` query parameter: ``` GET https://docs.iva.opencb.org/readme.md?ask= ``` The question should be specific, self-contained, and written in natural language. The response will contain a direct answer to the question and relevant excerpts and sources from the documentation. Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.